CORDIS provides links to public deliverables and publications of HORIZON projects.
Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .
Deliverables
Protocols will be developed for the collection, pre-processing and storage of blood, urine, exhaled breath and exhaled breath condensate samples to be incorporated in WP6 and 7 study protocols.
Report on the establishment of the EPHOR mega cohort (opens in new window)The EPHOR mega cohort will be created including cohorts with data on occupational histories Occupations will be coded including using automated free text mining developed in WP4 crosswalks between different coding systems will be developed and used to harmonize data across different occupational coding systems and versions together with WP4 and the newly developed EuroJEM WP2 will be applied to occupational histories over the lifecourse of included participants A framework for decentralized largescale pooling of data for epidemiological analyses will be implemented with WP4
Report on dynamic coding for more meaningful categories for exposure assessment (opens in new window)Improved coding systems will be developed and used in by WP2 for more flexible coding that allows for different coding structures depending on the risk factor.
Inventory of European cohorts with extensive information on occupational exposures (opens in new window)Extension and refinement of a searchable web-based database inventory of occupational cohorts based on the ongoing COST Action OMEGA-NET.
Protocol for feasibility study (opens in new window)Protocol for the feasibility study, that will be conducted in at least two countries with at least 12 participants, to test the exposure protocol including the wearable sensor system in the field. The exposure protocol will ultimately be applied in the case studies.
Report on the external exposome protocol development for the case studies (opens in new window)Development of a full external exposome protocol for in the case studies that will bring together the protocols on the wearable sensor system and passive sampling A protocol for field implementation informed consent forms data collection QAQC data management and data analysis will be developed with the case studies The protocol will also encompass a digital questionnaire on working time sleep specific chemical and physical exposures diet lifestyle workplace organisation psychosocial factors and jobrecords
Report on protocol for including new data in EuroJEM (opens in new window)To ensure that the dynamic EuroJEM includes the latest available information of highest quality possible a protocol will be developed for including new data into EuroJEM The protocol will include methods for searching and collecting new data from literature assisted by text mining WP4 exposure databases eg ECHA REACH database reports and Bayesian decision criteria to determine if and how to revise exposure estimates in the JEM This task will also investigate the use of optimized and dynamic coding systems
Report on tutorial on the use of hierarchical models in working-life exposome research (opens in new window)Hierarchical regression methods will be further developed and applied to the EPHOR mega cohort WP5 to identify new exposuredisease associations in the agnostic analyses and use the outcomes within WP2 to evaluate and improve EuroJEM
Report on harmonizing existing JEMs (opens in new window)Occupational codes will be harmonized Inconsistencies and gaps between different JEMs will be resolved by expert judgement leaving the possibility to keep betweencountry differences when factually motivated Imputation will be applied to cover missing values occupationscountries resulting in a first version of EuroJEM
Report on tutorial for the application of a suite of ‘multiple exposure methods' (opens in new window)Methods capable of handling multiple exposures in exposureresponse analyses will be developed This includes the conventional approach of analysing all exposureresponse associations in parallel while adjusting for multiple comparisons and novel methods based on machine learning approaches that account for the correlations between exposures
Report on inventory of ETR models relevant for EPHOR (opens in new window)An inventory will be compiled of all Compartmental multistate models twostage clonal expansion models and exposure rate models for ETR analyses that have been published to date This inventory will document what the underlying assumptions of these models are what inference they provide and to what extent they overlap
Protocol of study on working life exposome and respiratory health (opens in new window)A protocol will be developed for new data collection on respiratory health and working life exposome in 12 study centres from 7 European countries (Spain, France, Sweden, Norway, Estonia, Iceland, Denmark) and Australia.
Report on collection and defining JEMs (opens in new window)For each JEM information will be collected on coding systems of occupation and industry timeperiods covered and time intervals exposure indices and data sources For each exposure definitions of exposednonexposed will be suggested based on an agreed European background level of exposure and the unit of exposure to be used
Report on automated job coding (opens in new window)Improved methods for automated coding of free text fields in occupational histories into job coding will be developed based on artificial intelligence AI mimicking human experts for coding of occupational histories to be used in WP5
Report on methods and results passive sampling method (opens in new window)Protocol development for applying and analyzing passive sampling wristbands for chemical analyses and passive dust collection for biological analyses. Analyses and reporting on passive samples collected in the case studies.
Report on development of new and more specific JEMs (opens in new window)New partsdimensions for the EuroJEM will be developed to cover 1 selected exposures which for the same occupational code vary largely by industry eg mechanic maintenance or assembly worker or by gender eg job control physical work load 2 key emerging risks eg threats and violence at work 3 new concepts eg societal status of the work 4 employment conditions eg nonstandard temporarily in another country precarious and 5 key nonoccupational exposures lifestyle socioeconomic conditions will be addressed when countryspecific data are available by occupational code
Webbased toolbox version 10 including an interactive visualization tool several protocols for external and internal exposome assessment searchable databases of JEMs and populations
Publications
Author(s):
William Mueller, Alice Smith, Eelco Kuijpers, , Anjoeka Pronk, , Miranda Loh
Published in:
Annals of Work Exposures and Health, Issue xx, 2024, Page(s) 1-7, ISSN 2398-7308
Publisher:
Oxford Acedemic
DOI:
10.1093/annweh/wxae057
Author(s):
Eline Verscheure a, Rob Stierum b, Vivi Schlünssen c, Anne Mette Lund Würtz c, Dorian Vanneste a, Manolis Kogevinas d, Barbara N. Harding d, Karin Broberg e f, Shan Zienolddiny-Narui g, Johanna Samulin Erdem g, Mrinal K. Das g, Konstantinos C. Makris h, Corina Konstantinou h, Xanthi Andrianou h, Susan Dekkers b, Lorna Morris i 1, Anjoeka Pronk b, Lode Godderis a j 2, Manosij Ghosh a 2, of EPHOR
Published in:
Enviromental research, Issue 238; 1, 2023, Page(s) 117001, ISSN 0013-9351
Publisher:
Academic Press
DOI:
10.1016/j.envres.2023.117001
Author(s):
Annika M. Schoene; Ioannis Basinas; Martie van Tongeren; Sophia Ananiadou
Published in:
International Journal of Environmental Research and Public Health, Issue 19 (14), 2022, Page(s) 1-14, ISSN 1660-4601
Publisher:
MDPI (Multidisciplinary Digital Publishing Institute)
DOI:
10.3390/ijerph19148544
Author(s):
Svetlana Solovieva, Astrid de Wind, Karina Undem, Christian Dudel, Ingrid S. Mehlum, Swenne G. van den Heuvel, Suzan J. W. Robroek & Taina Leinonen
Published in:
BMC Public Health, Issue 24, 2024, Page(s) 735, ISSN 1471-2458
Publisher:
BioMed Central
DOI:
10.1186/s12889-024-18229-y
Author(s):
Hartikainen, E., Solovieva, S., Viikari-Juntura, E., & Leinonen, T.
Published in:
Scandinavian Journal of Work, Environment & Health, Issue 2023;49(1):23-32, 2023, Page(s) 23-32, ISSN 0355-3140
Publisher:
Nordic Association of Occupational Safety and Health (NOROSH)
DOI:
10.5271/sjweh.4054
Author(s):
Evi De Ryck; Manosij Ghosh; Tim S. Nawrot; Brigitte Reimann; Gudrun Koppen; Els Verachtert; Roland Devlieger; Lode Godderis; Sara Pauwels
Published in:
Environmental Pollution, Issue 346 (1), 2024, Page(s) 1, ISSN 0269-7491
Publisher:
Pergamon Press Ltd.
DOI:
10.1016/j.envpol.2024.123465
Author(s):
Pronk, Anjoeka; Loh, Miranda; Kuijpers, Eelco; Albin, Maria; Selander, Jenny; Godderis, Lode; Ghosh, Manosij; Vermeulen, Roel; Peters, Susan; Mehlum, Ingrid Sivesind; Turner, Michelle C.; Schlünssen, Vivi; Goldberg, Marcel; Kogevinas, Manolis; Harding, Barbara N.; Solovieva, Svetlana; Garani-Papadatos, Tina; van Tongeren, Martie; Stierum, Rob
Published in:
Environmental Epidemiology, Issue 2, 2022, ISSN 2474-7882
Publisher:
Wolters Kluwer Health
DOI:
10.1097/ee9.0000000000000185
Author(s):
López-Cervantes, J. P., Lønnebotn, M., Jogi, N. O., Calciano, L., Kuiper, I. N., Darby, M. G., Dharmage, S. C., Gómez-Real, F., Hammer, B., Bertelsen, R. J., Johannessen, A., Würtz, A. M. L., Mørkve Knudsen, T., Koplin, J., Pape, K., Skulstad, S. M., Timm, S., Tjalvin, G., Krauss-Etschmann, S., Accordini, S., … Svanes, C.
Published in:
International Journal of Environmental Research and Public Health, Issue 18 (23), 2021, Page(s) 12684, ISSN 1660-4601
Publisher:
MDPI
DOI:
10.3390/ijerph182312684
Author(s):
Susan Peters, Karina Undem, Svetlana Solovieva, Jenny Selander, Vivi Schlünssen, Karen M Oude Hengel, Maria Albin, Calvin B Ge, Katarina Kjellberg, Damien M McElvenny, Per Gustavsson, Henrik A Kolstad, Anne Mette L Würtz, Bendik C Brinchmann, Karin Broberg, Stine Fossum, Merete Bugge, Mette Wulf Christensen, Manosij Ghosh, David Høyrup Christiansen, Suzanne L Merkus, Lars-Kristian Lunde, Eira V
Published in:
Annals of Work Exposures and Health, Issue 68; 6, 2024, Page(s) 562-580, ISSN 2398-7308
Publisher:
Oxford Academic
DOI:
10.1093/annweh/wxae045
Author(s):
Oude Hengel KM, Burdorf A, Pronk A, Schlünssen V, Stokholm ZA, Kolstad HA, van Veldhoven K, Basinas I, van Tongeren M, Peters S
Published in:
Scand J Work Environ Health, Issue 48 (1), 2021, Page(s) 61-70, ISSN 0355-3140
Publisher:
Nordic Association of Occupational Safety and Health (NOROSH)
DOI:
10.5271/sjweh.3998
Author(s):
Alicia Guillien, Manosij Ghosh, Thomas Gille, Orianne Dumas
Published in:
Breathe, Issue 19, 2023, Page(s) 23044, ISSN 1810-6838
Publisher:
European Respiratory Society
DOI:
10.1183/20734735.0044-2023
Author(s):
Vivi Schlünssen, Jean Baptist du Prel, Martie van Tongeren, Lode Godderis, Michelle C Turner, and Damien McElvenny, OMEGA-NET COVID-19 Questionnaire Subtask Group
Published in:
Annals of Work Exposures and Health, Issue 67(1), 2023, Page(s) 4-8, ISSN 2398-7308
Publisher:
Oxford University Press
DOI:
10.1093/annweh/wxac044
Author(s):
Wenxin Wan, Calvin B Ge, Melissa C Friesen, Sarah J Locke, Daniel E Russ, Igor Burstyn, Christopher J O Baker, Anil Adisesh, Qing Lan, Nathaniel Rothman, Anke Huss, Martie van Tongeren, Roel Vermeulen, Susan Peters
Published in:
Annals of Work Exposures and Health, Issue 67; 5, 2023, Page(s) 663-672, ISSN 2398-7316
Publisher:
Oxford Academic
DOI:
10.1093/annweh/wxad002
Author(s):
Mathijs A. Langezaal; Egon L. van den Broek; Susan Peters; Marcel Goldberg; Grégoire Rey; Melissa C. Friesen; Sarah J. Locke; Nathaniel Rothman; Qing Lan; Roel C. H. Vermeulen
Published in:
Communications Medicine, Issue 3(1), 2023, Page(s) 160, ISSN 2730-664X
Publisher:
Springer Nature
DOI:
10.1038/s43856-023-00397-4
Author(s):
Verscheure, Eline; Schlünssen, Vivi; Broberg, Karin; Makris, Konstantinos; Charisiadis,Pantelis; Narui, Shan; Samulin Erdem, Johanna; Harding, Barbara; Kogevinas, Manolis; Samuel, Helen; Murch, William; Christie, Francesca; Schaber, Chad; Stierum, Rob; Pronk, Anjoeka; Godderis, Lode; Ghosh, Manosij
Published in:
2023
Publisher:
KUL
DOI:
10.48804/9s65kb
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