Developing an Artificial Intestine for the sustainable farming of healthy fish

Deliverables

Presumably around month 18 the consortium will have generated enough new data to be assembled in one or more scientific publications in open access peer reviewed journalsThis WP will continue until month 48 and beyond untill all results will be published

Proceedings of partecipation to and workshop organization in scientific conferences

Similarly to D33 all members will communicate theyr results in high level scientific meeting and whenever possible will organize specific workshop within such meetings with the aim to disseminate the results and stimulate a fruitful scientific discussion with Colleagues that do not belong to the project

Dissemination and Exploitation Plan

A Dissemination and Exploitation Plan will be prepared at the end of the first Reporting Period (RP1). It will be updated for the subsequent Reporting Periods.

Press release for milestone and special achievements 1

Preparation of Press release for milestone and special achievements on behalf of all Participants

Lab open days for school children and young adults 1

Each beneficiary will organize a lab open day either directly or through the initiatives of their own Institutions.

Production of display and demonstration material 1

Dissemination material will be produced and shared among partners

Participation to the Annual European Researchers night 1

Each year the project beneficiaries will be present at The European Researchers' Night closest to its location (each September).

Web-site, Facebook and Tweeter accounts

From the begining of the project and along its entire duration the partners will ensure a constant flow of information suitable for the general public in order to facilitate the interaction with the common citizens

Production of display and demonstration material 2

Dissemination material will be produced and shared among partners

Publications

Evaluation of rainbow trout (Oncorhynchus mykiss) organotypic intestinal platforms: cellular responses after long-term exposure to in vitro digested feed

Author(s): Verdile, Nicole Camin, Federica Chacon, Marcelo A. Pasquariello, Rolando Pavlovic, Radmila Peggs, David Fontanillas, Ramon Tandler, Amos Kortner, Trond M. Bitan, Amir Brevini, Tiziana A. L. Gandolfi, Fulvio
Published in: Frontiers in Marine Science, Issue Volume 10, 2023, Page(s) 1239682, ISSN 2296-7745
Publisher: Frontiers Media S.A.
DOI: 10.3389/fmars.2023.1239682

Telocytes: Active players in the rainbow trout (oncorhynchus mykiss) intestinal stem-cell niche

Author(s): Verdile, Nicole Pasquariello, Rolando Cardinaletti, Gloriana Tibaldi, Emilio Brevini, Tiziana A.L. Gandolfi, Fulvio
Published in: Animals, Issue 74, 12 (1), 2022, ISSN 2076-2615
Publisher: MDPI
DOI: 10.3390/ani12010074

Organ-on-Chip Approaches for Intestinal 3D In Vitro Modeling

Author(s): Joana Pimenta, Ricardo Ribeiro, Raquel Almeida, Pedro F. Costa, Marta A. da Silva, Bruno Pereira
Published in: Cellular and Molecular Gastroenterology and Hepatology, Issue 13, 2022, Page(s) 351-367, ISSN 2352-345X
Publisher: Elsevier Inc.
DOI: 10.1016/j.jcmgh.2021.08.015

Bile components affect the functions and transcriptome of the rainbow trout intestinal epithelial cell line RTgutGC

Author(s): Guro Løkka, Anusha K.S. Dhanasiri, Åshild Krogdahl, Trond M. Kortner
Published in: Fish & Shellfish Immunology, Issue 131, 2024, Page(s) 1144-1156, ISSN 1050-4648
Publisher: Academic Press
DOI: 10.1016/j.fsi.2022.10.049

Development of a Rainbow Trout (Oncorhynchus mykiss) Intestinal In Vitro Platform for Profiling Amino Acid Digestion and Absorption of a Complete Diet

Author(s): Pasquariello, Rolando Pavlovic, Radmila Chacon, Marcelo A. Camin, Federica Verdile, Nicole Løkka, Guro Panseri, Sara Faustini, Massimo Tandler, Amos Peggs, David Kortner, Trond M. Bitan, Amir Brevini, Tiziana .A.L. Gandolfi, Fulvio
Published in: Animals, Issue volume 13 Issue 14, 2023, Page(s) 2278-2298, ISSN 2076-2615
Publisher: MDPI
DOI: 10.3390/ani13142278

A fish intestinal in vitro model for investigation of lipid metabolism and steatosis

Author(s): Daphne Siciliani, Bente Ruyter, Guro Løkka, Kirsti Elisabeth Præsteng, Matteo Minghetti, Trond M. Kortner
Published in: Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, Issue 1870, 2024, Page(s) 159573, ISSN 1388-1981
Publisher: Elsevier BV
DOI: 10.1016/j.bbalip.2024.159573

Light-Based 3D Printing of Gelatin-Based Biomaterial Inks to Create a Physiologically Relevant In Vitro Fish Intestinal Model

Author(s): Anna Szabó, Rolando Pasquariello, Pedro F. Costa, Radmila Pavlovic, Indi Geurs, Koen Dewettinck, Chris Vervaet, Tiziana A. L. Brevini, Fulvio Gandolfi, Sandra Van Vlierberghe
Published in: Macromolecular Bioscience, Issue 2023, 2300016, 2023, Page(s) 1-11, ISSN 1616-5195
Publisher: Wiley-VCH GmbH,
DOI: 10.1002/mabi.202300016

The 3D Pattern of the Rainbow Trout (Oncorhynchus mykiss) Enterocytes and Intestinal Stem Cells

Author(s): Nicole Verdile, Rolando Pasquariello, Tiziana A. L. Brevini, Fulvio Gandolfi
Published in: International Journal of Molecular Sciences, Issue 21/23, 2020, Page(s) 9192, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21239192

Distinct Organotypic Platforms Modulate Rainbow Trout (Oncorhynchus mykiss) Intestinal Cell Differentiation In Vitro

Author(s): Verdile, Nicole Camin, Federica Pavlovic, Radmila Pasquariello, Rolando Stuknytė, Milda De Noni, Ivano Brevini, Tiziana A.L. Gandolfi, Fulvio
Published in: Cells, Issue Volume 12 Issue 14, 2023, Page(s) 1843, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells12141843

Cell-Interactive Gelatin-Based <sup>19</sup>F MRI Tracers: An <i>In Vitro</i> Proof-of-Concept Study

Author(s): Kristyna Kolouchova, Ondrej Groborz, Vit Herynek, Oleg V. Petrov, Jan Lang, David Dunlop, Laurens Parmentier, Anna Szabó, David Schaubroeck, Peter Adriaensens, Sandra Van Vlierberghe
Published in: Chemistry of Materials, Issue 36, 2024, Page(s) 183-196, ISSN 0897-4756
Publisher: American Chemical Society
DOI: 10.1021/acs.chemmater.3c01574

Effect of Porosity on the Colonization of Digital Light-Processed 3D Hydrogel Constructs toward the Development of a Functional Intestinal Model

Author(s): Anna Szabó, Elly De Vlieghere, Pedro F. Costa, Indi Geurs, Koen Dewettinck, Laure Maes, Debby Laukens, Sandra Van Vlierberghe
Published in: Biomacromolecules, Issue 25, 2024, Page(s) 2863-2874, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.4c00019

A Detailed Study of Rainbow Trout (Onchorhynchus mykiss) Intestine Revealed That Digestive and Absorptive Functions Are Not Linearly Distributed along Its Length

Author(s): Nicole Verdile, Rolando Pasquariello, Marco Scolari, Giulia Scirè, Tiziana A. L. Brevini, Fulvio Gandolfi
Published in: Animals, Issue 10/4, 2020, Page(s) 745, ISSN 2076-2615
Publisher: MDPI
DOI: 10.3390/ani10040745

Increasing hydrogel complexity from 2D towards 3D towards intestinal tissue engineering

Author(s): Anna Szabó, Elly De Vlieghere, Pedro F. Costa, Indi Geurs, Koen Dewettinck, Sandra Van Vlierberghe
Published in: Giant, Issue 16, 2023, Page(s) 100198, ISSN 2666-5425
Publisher: Elsevier Ltd
DOI: 10.1016/j.giant.2023.100198

New Stable Cell Lines Derived from the Proximal and Distal Intestine of Rainbow Trout (Oncorhynchus mykiss) Retain Several Properties Observed In Vivo

Author(s): Rolando Pasquariello, Nicole Verdile, Radmila Pavlovic, Sara Panseri, Kristin Schirmer, Tiziana A. L. Brevini, Fulvio Gandolfi
Published in: Cells, Issue 10/6, 2021, Page(s) 1555, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells10061555

Preparation of Biological Scaffolds and Primary Intestinal Epithelial Cells to Efficiently 3D Model the Fish Intestinal Mucosa

Author(s): Nicole Verdile, Anna Szabó, Rolando Pasquariello, Tiziana A. L. Brevini, Sandra Van Vlierberghe, Fulvio Gandolfi
Published in: Methods in Molecular Biology, Next Generation Culture Platforms for Reliable In Vitro Models, 2021, Page(s) 263-278
Publisher: Springer US
DOI: 10.1007/978-1-0716-1246-0_19

Preparation of Biological Scaffolds and Primary Intestinal Epithelial Cells to Efficiently 3D Model the Fish Intestinal Mucosa

Author(s): Nicole Verdile, Anna Szabó, Rolando Pasquariello, Tiziana A. L. Brevini, Sandra Van Vlierberghe, Fulvio Gandolfi
Published in: Next Generation Culture Platforms for Reliable In Vitro Models - Methods and Protocols, Issue 2273, 2021, Page(s) 263-278, ISBN 978-1-0716-1245-3
Publisher: Springer US
DOI: 10.1007/978-1-0716-1246-0_19#doi

Deliverables

Publications

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